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 Forum index » Archive » Archive: Perplex City » PXC: General/Updates
[UPDATE] PXCPD Internal Access - 14 Mar 06 - Cymbalisty File
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locqust
Unfettered


Joined: 14 Oct 2005
Posts: 545
Location: Gloucestershire UK

Well Im still hoping the JPG's of the reports and witness statements will give us something once I can de-stegg them. (that a word??)
But I am really having problems with this, I cant seem to get the process to work past identifiying which JPG's have a potential message inside them!
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PostPosted: Fri Mar 17, 2006 9:48 am
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modern_hero
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Joined: 22 Feb 2006
Posts: 159
Location: UK

jojojojo wrote:
They started at the library at exactly the same time, so this is perfectly feasible.


I see a research opportunity in the wings...

Can we e-mail everyone who's not too close to these people for information on their backgrounds?

OH!!! And if they turn out to be bag guys, we can have them arrested and then Kurt and Violett can have mad passionate... conversations... Laughing
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PostPosted: Fri Mar 17, 2006 9:58 am
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Weefz
Boot

Joined: 05 Mar 2006
Posts: 49
Location: London, UK

sledgecallier wrote:
My feeling is that the Ceretin is still just a red herring and that he died of something else and the ceretin was either used as a convenient cover-up drug or was just blindly assumed to be the cause of death by the police.


You think it was the neuro-inhibitor? Perhaps - he could have been hit by a stronger dose/shock/whatever than Pietro which sped things up a bit. We don't know the official cause (trigger) of death for Pietro, do we? Just had a look at the old Sentinel report which says:

Quote:
Doctors have not offered any guesses as to what precipitated Salk's neurological crisis, saying only that it was a private matter, and that only the patient's family could decide whether or not to reveal that information.


So perhaps they assumed it was an attempted suicide by Ceretin that went wrong. Ask Sylvia?
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PostPosted: Fri Mar 17, 2006 10:02 am
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The Wizard
Boot

Joined: 14 Jan 2006
Posts: 13

Been out the game for while but have some time due to a torn muscle in my back (ouch)

Thinking about this how about trying to locate the source of the black market ceretin, i.e. the dealer??

If we can get someone to make some enquiries regarding this and see if we can find the supplier and try and get some information out of them as to who has been buying off them???


Sorry if this has already been raised elsewhere..............

PostPosted: Fri Mar 17, 2006 10:13 am
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modern_hero
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Joined: 22 Feb 2006
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No, i don't think it's the same thing, as the two have opposite reactions.

From what I gather, Ceretin opens up pathways in the brain, alowing you to become smarter for a set time, whereas Neuro-inhibitors seem to shut them down?

So, ceretin = more brain, until it liquifies itself, Inhibitors = less brain, until it dissolves itself?

Different effects, same result?
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PostPosted: Fri Mar 17, 2006 10:19 am
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Weefz
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Joined: 05 Mar 2006
Posts: 49
Location: London, UK

modern_hero wrote:
No, i don't think it's the same thing, as the two have opposite reactions.

From what I gather, Ceretin opens up pathways in the brain, alowing you to become smarter for a set time, whereas Neuro-inhibitors seem to shut them down?

So, ceretin = more brain, until it liquifies itself, Inhibitors = less brain, until it dissolves itself?

Different effects, same result?


Hmm.. good point - it does say "synaptic overload" in the report. Nothing about degeneration, just "liquefactive necrosis"

So what else do we know that could cause that aside from Ceretin?
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PostPosted: Fri Mar 17, 2006 10:27 am
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modern_hero
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Joined: 22 Feb 2006
Posts: 159
Location: UK

Weefz wrote:
Hmm.. good point - it does say "synaptic overload" in the report. Nothing about degeneration, just "liquefactive necrosis"

So what else do we know that could cause that aside from Ceretin?


One too many nights cruising the forums? theoretically, if a minor power supply, such as one too many batteries, were commected to the cerebral cortez in just the right places, the resulting wave of electricity could also produce synaptic overload, although never proven...

Twisted Evil Time for some experimenting?
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I'm Perplexed...

PostPosted: Fri Mar 17, 2006 10:36 am
Last edited by modern_hero on Fri Mar 17, 2006 10:50 am; edited 1 time in total
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modern_hero
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OOh, just found a quotable...

Quote:
Dr. Tononi said that the hypothesis can lead to research to answer questions such as whether other learning tasks produce local increase of slow wave homeostasis during subsequence sleep. Research can show structural changes after sleep, such as weaker synapses and evoked potentials. Sleep deprivation should lead to symptoms of synaptic overload (e.g., brain areas that cannot function optimally). If the hypothesis is correct, it could lead to specific ideas about how to achieve good sleep. For example, drugs could be developed to increase sleep by promoting SWA, leading to downscaling.

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PostPosted: Fri Mar 17, 2006 10:40 am
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Weefz
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Joined: 05 Mar 2006
Posts: 49
Location: London, UK

modern_hero wrote:
Weefz wrote:
Hmm.. good point - it does say "synaptic overload" in the report. Nothing about degeneration, just "liquefactive necrosis"

So what else do we know that could cause that aside from Ceretin?


One too many nights cruising the forums? theoretically, if a minor power supply, such as one too many batteries, were commected to the cerebral cortez in just the right places, the resulting wave of electricity could also produce synaptic overload, although never proven...


Yeah, things start to blur together. I think I'll go do something nice and simple like watching Lost.

Would be a mighty good trick to get to his cerebral cortex without causing any other damage.

Sleep deprivation also unlikely - even with Ceretin to boost him people would still notice dark circles and other symptoms.

Confused
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PostPosted: Fri Mar 17, 2006 10:52 am
Last edited by Weefz on Fri Mar 17, 2006 10:58 am; edited 1 time in total
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modern_hero
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Joined: 22 Feb 2006
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Weefz wrote:
Sleep deprivation also unlikely - even with Ceretin to boost him people would still notice dark circles and other symptoms.


Nothing a pot of coffee and a bit of makeup couldn't disguise...

As for the lost thing? TV is a good idea. I'm off for a fag, coffee and some TV. Will come back with more conspiracy theories later...

/V\ Miranda = 'V'? Rolling Eyes
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PostPosted: Fri Mar 17, 2006 10:55 am
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CoolCats712
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Joined: 20 Feb 2006
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Location: Long Beach, CA

modern_hero wrote:
OOh, just found a quotable...

Quote:
Sleep deprivation should lead to symptoms of synaptic overload (e.g., brain areas that cannot function optimally).


Nice research, but unfortunately I think we're talking two different types of "synaptic overload" here. The kind produced by sleep deprivation is just a temporary fatiguing of the neurons. A person can go 5+ days without sleep and take a hit to their cognitive abilities, but there aren't any chronic deficits (like, say, death).

The report seems to be referring to "overload" as more of a fusebox analogy - not exactly proper terminology, but I guess when you're looking at a fried brain it seems apropos. Ceretin works by strengthening synaptic connections, so an overdose (from what people have suggested before) would cement these connections, creating closed circuits in the brain and scrambling it like an egg. This does sound quite distinct from inhibition, which, if it really does work like a neurodegenerative, would cause apoptosis in the neurons and glial cells and create plaques which hinder neural performance. If it's got another mechanism, however, I've got no clue what to look for. I would kill for a brain scan right now!

PostPosted: Fri Mar 17, 2006 1:29 pm
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Centipede
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Joined: 17 Sep 2004
Posts: 439
Location: Bronx, NY

I'm wondering if the Ceretin was just a means to cover the actual chemicals used in his murder. Tetrodotoxin is a neurotoxin (from blowfish) that is lethal in miniscule doses which wouldn't necessarily be tested for (especially with the Ceretin overdose staring you in the face). We don't know much about Ceretin and the symptoms of overdose, so it's possible that the damage caused by a neurotoxin like Tetrodotoxin could be the same as a Ceretin overdose. Since Tetrodotoxin is an organic toxin, it would be undetectable if fully metabolised as well.

http://www.emedicine.com/EMERG/topic576.htm wrote:
Tetrodotoxin is a heat-stable (except in alkaline environments) and water-soluble nonprotein.

Tetrodotoxin is a heterocyclic, small, organic molecule that acts directly on the electrically active sodium channel in nerve tissue (see Image 2). Tetrodotoxin blocks diffusion of sodium through the sodium channel, preventing depolarization and propagation of action potentials in nerve cells.

All of the observed toxicity is secondary to the action potential blockade. Tetrodotoxin acts on the central and the peripheral nervous systems (ie, autonomic, motor, sensory nerves).

Tetrodotoxin also stimulates the chemoreceptor trigger zone in the medulla oblongata and depresses the respiratory and vasomotor centers in that area.

The first symptoms occur 15 minutes to several hours postingestion of tetrodotoxin-containing food. A recent report on toxicity found that initial symptoms may occur up to 20 hours after ingestion.

Patients with severe toxicity may have deep coma, fixed nonreactive pupils, apnea, and loss of all brain stem reflexes.


I'm not sure what all the technical bits mean, so I defer to someone with more medical type experience. Is this plausible?

PostPosted: Fri Mar 17, 2006 1:55 pm
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modern_hero
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Joined: 22 Feb 2006
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CoolCats712 wrote:
A person can go 5+ days without sleep and take a hit to their cognitive abilities, but there aren't any chronic deficits (like, say, death).


Lol. Yep, you get a full 11 days without sleep for crazyness and 15 before death.
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PostPosted: Fri Mar 17, 2006 2:04 pm
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Uhtoff
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Joined: 09 Dec 2005
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Think tetrodotoxin is unlikely - it's quite a polar molecule and iirc it doesn't pass the blood-brain barrier. It works by stopping your nerves conducting, but doesn't affect the metabolism of the nerves per se. So although it may well paralyze you completely (and hence you'd die because you couldn't breathe) it's unlkely to produce the kind of necrosis we're trying to explain as it doesn't kill the nerves, just makes them not work (and I'm pretty sure it doesn't get into the brain itself Wink).

PostPosted: Fri Mar 17, 2006 2:19 pm
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CoolCats712
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Joined: 20 Feb 2006
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Location: Long Beach, CA

I like Centipede's idea. I'm sure there's a ton of potentially deadly, difficult-to-trace chemicals lurking in Perplex City's fauna. The only thing is, with so much Ceretin in his system in so many places (eyeballs?) it had to have been ingested at least several hours before death in order to circulate, even if it wasn't the cause of death. Maybe just something to paralyze him, then force-feed?

My vote: Miranda seduced him (ergo no pants), slipped him a tranq, maybe a neurotoxin, then stuffed him full of Ceretin til he popped. A 3P cleanup crew then arrived and set up the suicide props. Maybe that dark liquid in his stomach was a glass of wine?

PostPosted: Fri Mar 17, 2006 2:20 pm
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